Radical Prostatectomy for High-risk Prostate Cancer: A Canadian Experience
CUA Online Library. Ischia J. 06/24/13; 31225; MP-01.06
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Abstract
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Radiation Oncologists have taken the initiative by performing several well-conducted randomized trials for men with clinically localized high-risk prostate cancer which has lead to a decrease in the proportion of men who receive surgery as their primary treatment. However, the advantages of surgery are multiple, and importantly, around half of men can avoid ADT. The objective of this study is to report on the biochemical progression-free outcomes of radical prostatectomy in men with high-risk localized prostate cancer.
The overall 5 and 10-year bPFS were 60% and 50%, respectively. On multivariate analysis, only biopsy Gleason score and the number of risk factors were independent predictors of bPFS.
Radical prostatectomy should be considered a primary treatment option in men with high-risk localized prostate cancer. Around half of men with very high-risk disease will be cured with radical prostatectomy as the primary (and often only) component of their initial treatment.
The overall 5 and 10-year bPFS were 60% and 50%, respectively. On multivariate analysis, only biopsy Gleason score and the number of risk factors were independent predictors of bPFS.
Radical prostatectomy should be considered a primary treatment option in men with high-risk localized prostate cancer. Around half of men with very high-risk disease will be cured with radical prostatectomy as the primary (and often only) component of their initial treatment.
Radiation Oncologists have taken the initiative by performing several well-conducted randomized trials for men with clinically localized high-risk prostate cancer which has lead to a decrease in the proportion of men who receive surgery as their primary treatment. However, the advantages of surgery are multiple, and importantly, around half of men can avoid ADT. The objective of this study is to report on the biochemical progression-free outcomes of radical prostatectomy in men with high-risk localized prostate cancer.
The overall 5 and 10-year bPFS were 60% and 50%, respectively. On multivariate analysis, only biopsy Gleason score and the number of risk factors were independent predictors of bPFS.
Radical prostatectomy should be considered a primary treatment option in men with high-risk localized prostate cancer. Around half of men with very high-risk disease will be cured with radical prostatectomy as the primary (and often only) component of their initial treatment.
The overall 5 and 10-year bPFS were 60% and 50%, respectively. On multivariate analysis, only biopsy Gleason score and the number of risk factors were independent predictors of bPFS.
Radical prostatectomy should be considered a primary treatment option in men with high-risk localized prostate cancer. Around half of men with very high-risk disease will be cured with radical prostatectomy as the primary (and often only) component of their initial treatment.
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